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Ratain, Mark J.

One or more keywords matched the following items that are connected to Ratain, Mark J.

Item Type	Name
Concept	Clinical Trials, Phase I as Topic
Concept	Clinical Trials, Phase II as Topic
Concept	Clinical Trials, Phase III as Topic
Academic Article	Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents.
Academic Article	Phase I clinical and pharmacology study of 502U83 given as a 24-h continuous intravenous infusion.
Academic Article	Phase I study of suramin administered by intermittent infusion without adaptive control to cancer patients: update of two expanded dose levels near the maximally tolerated dose.
Academic Article	Ethical issues in phase I oncology research: a comparison of investigators and institutional review board chairpersons.
Academic Article	Data modifications to phase I study of suramin.
Academic Article	New phase I trial methodology.
Academic Article	Learning from our patients: one participant's impact on clinical trial research and informed consent.
Academic Article	Study of cohort-specific consent and patient control in phase I cancer trials.
Academic Article	Promising new agents in oncologic treatment.
Academic Article	Flavopiridol metabolism in cancer patients is associated with the occurrence of diarrhea.
Academic Article	Rationale for phase I study of UFT plus leucovorin and oral JM-216.
Academic Article	Anticancer agents targeting signaling molecules and cancer cell environment: challenges for drug development?
Academic Article	Endostatin: are the 2 years up yet?
Academic Article	Troxacitabine in patients with refractory leukemia.
Academic Article	Estimation of the glomerular filtration rate in cancer patients: a new formula for new drugs.
Academic Article	Phase II oncology trials: let's be positive.
Academic Article	Randomized phase II trials and prostate-specific antigen endpoints in prostate cancer: much ado about nothing?
Academic Article	Clarification regarding "phase II trials published in 2002: a cross-specialty comparison showing significant design differences between oncology trials and other medical specialties" and the accompanying commentary, "phase II cancer trials: out of control?".
Academic Article	Phase II trials published in 2002: a cross-specialty comparison showing significant design differences between oncology trials and other medical specialties.
Academic Article	Inside information: Financial conflicts of interest for research subjects in early phase clinical trials.
Academic Article	Design of phase II cancer trials using a continuous endpoint of change in tumor size: application to a study of sorafenib and erlotinib in non small-cell lung cancer.
Academic Article	EGFR pharmacogenomics: the story continues to mutate and evolve.
Academic Article	The design of phase II clinical trials testing cancer therapeutics: consensus recommendations from the clinical trial design task force of the national cancer institute investigational drug steering committee.
Academic Article	Testing the wrong hypothesis in phase II oncology trials: there is a better alternative.
Academic Article	Other paradigms: better treatments are identified by better trials: the value of randomized phase II studies.
Academic Article	Evaluating the activity of temsirolimus in neuroendocrine cancer.
Academic Article	Complementary and alternative medicine among advanced cancer patients enrolled on phase I trials: a study of prognosis, quality of life, and preferences for decision making.
Academic Article	Biomarkers in phase I oncology trials: signal, noise, or expensive distraction?
Academic Article	Optimising the design of phase II oncology trials: the importance of randomisation.
Academic Article	Prognostic factors for survival in patients treated in phase I clinical trials.
Academic Article	Resampling phase III data to assess phase II trial designs and endpoints.
Academic Article	A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
Academic Article	Randomized phase II trials: a long-term investment with promising returns.
Academic Article	Pushing the envelope: informed consent in phase I trials.
Academic Article	Dose-escalation models for combination phase I trials in oncology.
Academic Article	Analysis of the yield of phase II combination therapy trials in medical oncology.
Academic Article	Might cigarettes be a "smoking gun" to reduce taxane myelotoxicity?
Academic Article	Perceptions of cancer patients and their physicians involved in phase I trials.
Academic Article	Physician-determined patient risk of toxic effects: impact on enrollment and decision making in phase I cancer trials.
Academic Article	Estimation of renal cell carcinoma treatment effects from disease progression modeling.
Academic Article	Design of phase I combination trials: recommendations of the Clinical Trial Design Task Force of the NCI Investigational Drug Steering Committee.
Academic Article	Targeted therapies: redefining the primary objective of phase I oncology trials.
Academic Article	Bevacizumab and the risk of arterial and venous thromboembolism in patients with metastatic, castration-resistant prostate cancer treated on Cancer and Leukemia Group B (CALGB) 90401 (Alliance).
Academic Article	Evaluation of utility of pharmacokinetic studies in phase I trials of two oncology drugs.
Academic Article	A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
Academic Article	Participation in Cancer Pharmacogenomic Studies: A Study of 8456 Patients Registered to Clinical Trials in the Cancer and Leukemia Group B (Alliance).
Academic Article	Harmonization of Renal Function Assessment Is Needed During Early Clinical Development of Oncology Drugs.
Academic Article	Analysis of Impact of Post-Treatment Biopsies in Phase I Clinical Trials.
Academic Article	Taking a Measured Approach to Toxicity Data in Phase I Oncology Clinical Trials.
Academic Article	Casting doubt on the scientific utility of post-treatment biopsies in phase 1 trials.
Academic Article	Do Patients With Advanced Cancer Have the Ability to Make Informed Decisions for Participation in Phase I Clinical Trials?
Academic Article	Oncology phase I trial design and conduct: time for a change - MDICT Guidelines 2022.

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Clinical Trials Phase IV as Topic